mucoderm®

3D soft tissue graft

mucoderm® is a natural type I/III collagen matrix derived from porcine dermis that undergoes a multi-stage purification process, which removes all potential immunogens. The remaining matrix is a membrane that consists of collagen and elastin. mucoderm® promotes the revascularization and fast soft tissue integration and is a valid alternative to the patient’s own connective tissue.

Soft tissue augmentation
Covering of extraction sockets
Gingival recessions
Soft tissue grafting in combination with GBR/GTR
Broadening of attached gingiva

Immobilization	Contact of mucoderm® with the periosteal wound bed and immobilization should be ensured by suturing the matrix to the periosteum using single-interrupted- or all-crossed sutures
Avoid sharp edges	Cutting the edges of a shortly rehydrated matrix prevent damage of the gingival tissue during flap closure
Tunnel technique	For the tunnel technique a prolonged, 10-20 min, rehydration time of the mucoderm® is recommended. Fixation of the matrix by single-interrupted- or allcrossed sutures is required.
Gingival recessions	Exposure of the mucoderm® matrix should always be avoided in recession coverage procedures. Make sure that the repositioned flap completely covers the mucoderm® matrix. Achieving primary closure over the mucoderm® graft allows blood vessels to penetrate and incorporate the soft tissue graft material. Early exposure may lead to soft tissue graft failure.
Straumann® Emdogain®	Gingival recessions may be treated using mucoderm® and Straumann® Emdogain® together in a single approach. Potential benefits of adding Straumann® Emdogain® to a root coverage procedure with mucoderm® are described in "Collagen matrix and enamel matrix derivative". Make always sure that Straumann® Emdogain® is applied all over the root surfaces before the mucoderm® matrix is placed over the roots.

cerabone® and mucoderm® for immediacy in esthetic zone -Dr. M Motta

Initial view of the case. Discoloration of 1.1 and mild class I gingival recession

Treatment of single gingival recession with mucoderm® – Dr. A. Hamdy

botiss mucoderm® for treatment of single gingival recession - Clinical case

Initial clinical situation with Miller class 1 recession

Peri-implant soft tissue thickening with mucoderm® - Dr. F. Rojas-Vizcaya

Drilling template for guided implant placement

Tooth extraction and socket sealing with mucoderm® - Dr. A. Rossi

Initial clinical situation showing strongly compromised tooth 21

Isolated gingival recessions treated with the coronally advanced flap in conjunction with mucoderm® and Straumann® Emdogain® - Prof. Dr. Mario Taba Jr

Isolated gingival recessions treated by CAF in conjunction with mucoderm® and Straumann® Emdogain® - Taba Jr

Pre-surgical clinical situation. Deep gingival recessions at both upper canine.

Multiple gingival recessions treated with the modified coronally advanced flap in conjunction with mucoderm® and Straumann® Emdogain® - Dr. D. B. Hangyási

Multiple gingival recessions treated by MCAF in conjunction with mucoderm® and Straumann® Emdogain® - Hangyási

Pre-surgical situation. Multiple adjacent gingival recessions at teeth 12, 13 and 14.

Multiple gingival recessions treated with the modified coronally advanced flap in conjunction with mucoderm® - PD Dr. S. Hägewald

Multiple gingival recessions treated by MCAF in conjunction with mucoderm® - Hägewald

Multiple adjacent gingival recessions.

Soft tissue augmentation and GBR with mucoderm® and maxresorb® - Dr. S. Scherg

Soft tissue augmentation with GBR-Scherg

X-ray shows a 3-dimensional periondontal defect

Augmentation of the keratinized tissue in the posterior maxilla with mucoderm®- Dr. Dr. A. Stricker

Augmentation of the maxillary attached gingiva-Stricker

Initial clinical situation with lack of keratinized tissue

Ridge augmentation in the maxilla with maxgraft® bonebuilder in the aesthetic zone - Dr. M. Kristensen

Bone defect in area 11-21 due to two lost implants (periimplantitis) after 15 years of function

Socket seal with mucoderm® punch - Dr. G. Muhle

Intact socket following atraumatic tooth extraction

Multiple gingival recessions treated with the modified coronally advanced flap in conjunction with mucoderm® - Prof. Dr. Dr. A. Kasaj

Multiple gingival recessions treated by MCAF in conjunction with mucoderm® - Kasaj

Pre-surgical clinical situation. Multiple adjacent gingival recessions at teeth 12,13 and 14.

Multiple gingival recessions treated with the coronally advanced flap in conjunction with mucoderm® and Straumann® Emdogain® - Prof. Dr. Dr. A. Kasaj

Multiple gingival recessions treated by CAF in conjunction with mucoderm® and Straumann® Emdogain® - Kasaj

Pre-operative clinical view. Multiple adjacent gingival recessions.

Pre-prosthetic soft tissue augmentation of the ridge contour with mucoderm®- Dr. F. Rathe

Pre-prosthetic soft tissue augmentation of the ridge contour- Rathe

Initial clinical situation

Multiple gingival recessions treated with the modified coronally advanced tunnel in conjunction with mucoderm® and Straumann® Emdogain® - Dr. F. Rathe (2)

Multiple gingival recessions treated by MCAT with mucoderm® and Straumann® Emdogain® (2) - Rathe

Pre-operative clinical situation. Shallow multiple adjacent gingival recessions in the first quadrant.

Multiple gingival recessions treated with the modified coronally advanced tunnel in conjunction with mucoderm® - Dr. D. Rakasevic & Prof. Dr. S. Jankovic

botiss-mucoderm-recession-coverage-Rakasevic-1

Multiple adjacent recessions in the upper jaw.

Immediate implantation with maxresorb® - Dr. M. Frosecchi

X-ray control before tooth extraction

maxgraft® cortico at free-end situation in the mandible - J. Kielhorn

Clinical situation

Ridge preservation with maxgraft®, mucoderm® & Jason® membrane - Dr. F. Rojas-Vizcaya

Ridge preservation with maxgraft®, mucoderm® and Jason® membrane - Dr. Fernando Rojas-Vizcaya

Situation before extraction of the teeth

Ridge augmentation with maxgraft® bonebuilder and vestibuloplasty with mucoderm® in the maxilla – Dres. O.Blume/M.Back

botiss maxgraft® bonebuilder and vestibuloplasty with mucoderm® for ridge augmentation - Clinical case

Preoperative situation – Maxillary defect in area 14-16 (loss of implant 16 due to periimplantitis, tooth 14 extracted recently and area 15 already edentulous for a while)

mucoderm® for regeneration following the removal of an odontogenic fibroma - Prof. Dr. Dr. D. Rothamel

Regeneration with mucoderm® after fibroma resection

Initial clinical situation shows an odontogenic fibroma that was growing for years

Vertical bone augmentation and broadening of attached gingiva using cerabone®, permamem® and mucoderm® - Dr. R. Naimoli

Initial clinical situation with pronounced vertical and horizontal bone defect

cerabone® and mucoderm® for immediate implantation in the aesthetic area - Dr. D. Robles

Initial clinical situation - Central incisors with dental destruction and periapical pathology

Mucosal thickening around bone level implants - Dr. A. Puisys

Full-thickness flap preparation bucally and lingually

GBR and soft tissue augmentation with cerabone® and mucoderm® - H. Maghaireh & V. Ivancheva

Initial situation: missing teeth #11 & 12 and badly broken #21 root

“Poncho technique” with mucoderm® and Straumann® Emdogain® for peri-implant soft tissue augmentation - Dr. A. Puišys, Dr. E. Vindašiūtė-Narbutė, Dr. T. Linkevičius

Pre-operative situation.

Socket augmentation using mucoderm®, maxgraft® and Straumann® Emdogain® - Dr. A. Puišys

Alveolar socket before soft and hard tissue augmentation

Multiple recession coverage using MCAT in conjunction with mucoderm® and Emdogain® - Dr. D. Rakasevic

Pre-operative situation.

Multiple gingival recessions treated with the modified coronally advanced tunnel in conjunction with mucoderm® - Dr. R. Cosgarea & Prof. Dr. Dr. A. Sculean

Multiple gingival recessions treated by MCAT in conjunction with mucoderm® - Cosgarea & Sculean

Situation before surgery.

Treatment of an endo-perio-lesion and soft tissue augmentation with mucoderm® - Dr. A. Eslava Vanegas

Clinical situation before surgery

Soft tissue augmentation around missing lateral incisors with mucoderm® - Dr. V. Mirisola di Torresanto

Soft tissue augmentation around missing lateral incisors- Mirisola

Initial clinical situation

Augmentation of a traumatic soft tissue defect with mucoderm® - Dr. F. Rathe

Augmentation of a traumatic soft tissue defect-Rathe

Initial clinical situation with traumatic loss of tooth 21

GBR together with soft tissue augmentation with mucoderm® and maxresorb® - Dr. S. Scherg

GBR together with soft tissue augmentation with mucoderm® and maxresorb® - Scherg

Longitudinal fracture on the root resected tooth 21 with visible buccal fistula

Sealing of a postextraction socket with mucoderm® - Dr. M. Frosecchi

Post extraction socket sealing with mucoderm® - Dr. M. Frosecchi

X-ray showing endodontic failure of the molar

Single gingival recession treated with the coronally advanced flap in conjunction with mucoderm® - Prof. Dr. Dr. A. Kasaj

Single gingival recession treated by CAF in conjunction with mucoderm® - Kasaj

Pre-operative clinical situation. Gingival recession at the first premolar.

Multiple gingival recessions treated with the modified coronally advanced tunnel in conjunction with mucoderm® - Dr. A. Puisys

Baseline clinical situation, frontal view.

Ridge splitting and gingival contour augmentation with mucoderm® - Dr. F. Rathe

Soft tissue augmentation following ridge splitting- Rathe

Initial clinical situation with narrow ridge

Multiple gingival recessions treated with the modified coronally advanced flap in conjunction with mucoderm®, Straumann® Emdogain® and autologous CTG - Dr. F. Benvenuto

Multiple gingival recessions treated by MCAF in conjunction with mucoderm®, Straumann® Emdogain® and CTG - Benvenuto

Pre-operative clinical situation. Multiple adjacent gingival recessions.

Block augmentation with maxgraft® block & mucoderm® - Dr. K. Chmielewski

Block augmentation with maxgraft® block and mucoderm® - Dr. K. Chmielewski

Initial situation before surgery. Patient lost central incisors 1 month ago due to endodontic failures

Socket preservation with maxresorb® and mucoderm® - Dr. M. Frosecchi

Clinical situation before extraction

Regenerative corticotomy to compensate lower incisor malocclusion with cerabone® and mucoderm® - Dr. F. Brugnami & Dr. S. Meuli

Initial view of the clinical case: Class III malocclusion
Treatment plan: Regenerative corticotomy (PAOO)

Soft tissue thickening with mucoderm® - Dr. G. de Deus

Initial clinical view of the case. Soft tissue dehiscence around implants 26.

Ridge reconstruction with maxgraft® block in the posterior maxilla - Dr. A. Puišys

Initial situation displaying insufficient bone width

Hard and soft tissue management in immediate restoration in the esthetic area with partial edentulism- Dr. M. Frosecchi

Initial clinical situation

Simultaneous implantation and ridge augmentation using maxgraft® cortico, maxgraft® granules and mucoderm® - Dr. A. Puišys

Occlusal view of attached maxgraft® cortico at the buccal site

Excellent aesthetic result of buccal augmentation with mucoderm® and maxgraft® after immediate implant placement - 3-years follow-up - Dr. A. Puišys

Initial situation

Peri-implant soft tissue augmentation for pontic with mucoderm® - Dr. M. Frosecchi

Peri-implant soft tissue augmentation for pontic-Frosecchi

X-ray of initial clinical situation

Soft tissue thickening at early implant placement and GBR with mucoderm® and maxgraft® - Dr. A. Puisys

Soft tissue thickening at early implant placement-Puisys

Initial clinical situation

Soft tissue thickening at immediate implant placement and GBR with mucoderm® and maxgraft® - Dr. A. Puisys

Soft tissue thickening at immediate implant placement with GBR - Dr. A. Puisys

Initial clinical situation

Multiple recession coverage with mucoderm® and Straumann® Emdogain® - 4 year follow-up - Prof. G. Zucchelli & Dr. M. Stefanini

Multiple recession coverage with mucoderm® - Prof. G. Zucchelli & Dr. M. Stefanini

Initial clinical situation

Multiple gingival recessions treated with the modified coronally advanced tunnel in conjunction with mucoderm® and Straumann® Emdogain® - Dr. F. Rathe (1)

Multiple gingival recessions treated by MCAT in conjunction with mucoderm® and Straumann® Emdogain® (1) - Rathe

Pre-operative clinical situation. Gingival recessions at teeth 11 and 21.

Single gingival recession treated with the envelope technique in conjunction with mucoderm® - Prof. Dr. Dr. A. Kasaj

Single gingival recession treated with the envelope technique in conjunction with mucoderm® - Kasaj

Gingival recession at tooth 13. Free gingival graft (FGG) of a previous surgery for root coverage visible.

Immediate implant placement with cerabone® and mucoderm® - Dr. F. Rossi

recession on tooth 11

mucoderm® for full arch reconstruction of insufficient vestibular depth and lack of keratinized tissues - Dr. B. Mólnar & Prof. P. Windisch

Full arch reconstruction with lack of keratinised tissues-Mólnar/Windisch

Insufficient keratinized mucosa and extremely shallow vestibule on the maxilla

mucoderm® for soft tissue augmentation after resective surgery - Dr. Dr. P. Kämmerer

Soft tissue augmentation after resective surgery- Kämmerer

Initial clinical situation

Sealing of an extraction socket with mucoderm® - Dr. M. Frosecchi

Socket seal surgery with mucoderm® - Dr. M. Frosecchi

Tooth extraction due to root fracture

Widening of the peri-implant keratinized mucosa in the upper jaw with mucoderm®- Dr. A. Horváth

Widening of the peri-implant keratinized mucosa-Horváth

Lack of sufficient keratinized mucosa following extensive horizontal ridge augmentation

Multiple gingival recessions treated with the modified coronally advanced tunnel in conjunction with mucoderm® and Straumann® Emdogain® - Dr. D. B. Hangyási

Multiple gingival recessions treated by MCAT in conjunction with mucoderm® and Straumann® Emdogain® - Hangyási

Pre-operative clinical situation.

Treatment of a soft tissue deficiency with mucoderm® - Dr. F. Rojas-Vizcaya

Initial clinical situation showing severe soft tissue loss

Gingival contour augmentation and recession coverage with cerabone®, mucoderm® and Straumann® Emdogain®- Dr. D. B. Hangyási

Initial clinical situation

Multiple gingival recessions treated with mucoderm® - Dr. S. Stavar

botiss mucoderm® for coverage of multiple recessions - clinical case by Dr. S. Stavar

Initial clinical situation. Multiple adjacent gingival recessions in regio 11-13.

Soft tissue augmentation with mucoderm® for pontic - Dr. S. Stavar

botiss mucoderm® in soft tissue augmentation for pontic- Stavar

Initial clinical situation

Socket seal with mucoderm® for later implant placement - Dr. M. Back

Socket seal with mucoderm® for later implant placement - Dr. Michael Back

Extraction of tooth 44

Restoration of all four incisors with maxgraft® bonebuilder - Dr. Dr. Dr. O. Blume

botiss maxgraft® bonebuilder aesthetic reconstruction - Clinical case

Pre-operative clinical situation: changed color in the gingiva in the front maxilla

Application of mucoderm® for soft tissue management around single implants at second stage surgery Dr. C. De Annuntiis

mucoderm® around single implant at second stage surgery

Initial clinical situation showing tooth 45 not worth preserving

Horizontal GBR using permamem®, cerabone® and maxgraft® granules and soft tissue augmentation with mucoderm® - Dres. H. Maghaireh and V. Ivancheva

botiss-cerabone-permamem-maxgraft-mucoderm-horizontal-gbr-maghaireh

Initial situation - A young female 34 years old lost her front teeth in an surfing accident and she had a 5 unit bridge supported by her upper left lateral and right canine. The restoration failed and both supporting crowns have exposed and leaking margins.

Bone regeneration and implant-supported rehabilitation of a periodontally involved incisor - Dr. A. Eslava Vanegas

botiss cerabone and mucoderm for bone regeneration and implant supported rehabilitation of a periodontally involved incisor - clinical case

Initial clinical situation

GBR with simultaneous implant placement and widening of KM with mucoderm® - Dr. M. Blašković

GBR and widening of the keratinized mucosa with mucoderm® - Clinical Case by Dr. M. Blaskovic

Clinical view 8 weeks after extraction of teeth 25 and 26

Peri-implant soft tissue thickening after ridge augmentation with cerabone® and Jason® membrane - Dr. G. Moreira

Tooth 11 with mobility

Rapid revascularization and integration
Soft tissue replacement without palatal autograft harvesting
Complete remodeling into patient’s own tissue
Resorption time approx. 6-9 months
Can be easily applied and fixed
Can be cut to shape for specific procedures
Thickness approx. 1.2-1.7mm

Art. -No.	Size	Content
701520	15x20	1 matrix
702030	20x30	1 matrix
703040	30x40	1 matrix

For information on your local contact person please email to product-management@botiss.com

Videos

Soft tissue augmentation using mucoderm® (2-year follow up) - live surgery by Dr. A. Pandolfi

Soft tissue thickening on pig jaw by PD Dr. Dr. D. Rothamel

Socket seal on pig jaw by PD Dr. Dr. D. Rothamel

Recession coverage using the MCAT technique and mucoderm® - live surgery by Dr. F. Rathe

Vestibuloplasty on pig jaw by PD Dr. Dr. D. Rothamel

Recession coverage using the MCAT technique in conjunction with mucoderm® and Straumann® Emdogain®- live surgery by Dr. F. Rathe

Corrosion preparation showing vascular network running through the mucoderm® matrix

mucoderm® - 3D soft tissue graft

After placement, the patient’s blood infiltrates the mucoderm® graft through the three-dimensional soft tissue network, bringing host cells to the soft tissue graft surface and triggering the revascularization process. A significant revascularization may begin after the implantation depending on the health condition of the patient. mucoderm® offers a safe alternative to autologous connective tissue, suitable for a diverse range of soft tissue grafting indications.

Product Brochure:

mucoderm® - 3D-REGENERATIVE TISSUE GRAFT

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